Undergraduate or Master's Research Assistant

About the Karr Lab

Despite the explosion of data, we do not understand the details of how phenotype arises from genotype and the environment. We are developing whole-cell computational models which aim to comprehensively predict how cell behavior emerges from the molecular level by representing all of the biochemical activity inside cells. Our goal is to use whole-cell models to transform bioengineering and medicine into rigorous, quantitative disciplines. For example, whole-cell models could enable bioengineers to design microbial genomes for a variety of industrial applications, as well as enable physicians to tailor medical therapy to individual patients. Our research is highly interdisciplinary, involving systems biology, genomics, bioinformatics, data integration, numerical simulation, software engineering, and data visualization, and team-oriented.

About the Institute for Genomics & Multiscale Biology and the Icahn School of Medicine at Mount Sinai

The Karr Lab is a member of the Icahn Institute for Genomics & Multiscale Biology at the Icahn School of Medicine at Mount Sinai . The Icahn Institute aims to bring genomic technologies together with computational analyses to discover new disease mechanisms, develop new diagnostics, and identify new drug targets. The institute is a collaborative and interdisciplinary environment.

The Icahn School of Medicine at Mount Sinai is a superb environment for translational research and training. The school's multidisciplinary research institutes foster seamless collaboration with clinicians.


The student will help develop detailed computational models of individual cells and/or tools for building and simulating models of cells. This may include aggregating and organizing data; designing, testing, and calibrating models; and/or developing software tools to accelerate these tasks. The student will also have opportunities to participate in group meetings and attend seminars. The student will work closely with one of our faculty or postdoctoral fellows.

Desired skills/experience

Whole-cell modeling is highly interdisciplinary. Consequently, we're looking for team members with a broad range of relevant skills.

  • Strong interest in computational modeling;
  • Broad knowledge of biology and computer programming;
  • Abilities to solve challenging problems; and
  • Major in systems biology, computational biology, bioinformatics or a related field.

Dates and duration

Start and end dates are flexible. Summer internships will last 10-12 weeks and winter internships will last 3-4 weeks.


Summer interns will receive a stipend.


Unfortunately, we are not able to offer housing.

Career development, recreation, benefits, and compensation

Mount Sinai offers numerous opportunities for career development, as well as competitive benefits. Compensation will be commensurate with experience. Please see the links below for more information.

  • Staff
    • Benefits
    • Recreation programs
  • Postdoctoral scholars
    • Career development programs
    • Benefits
    • Subsidized housing
    • Recreation programs
  • Graduate students
    • PhD programs
    • Student organizations
    • Recreation programs
    • Subsidized housing

How to apply

Postdoctoral fellows and staff: Email a cover letter and CV to Jonathan .

Graduate students: Email a cover letter and CV to Jonathan , and apply to one of Mount Sinai's graduate programs . PhD applications are due December 1 each year to start the following September.

Undergraduate students: Email a cover letter and CV to Jonathan and, if eligible, apply to the Mount Sinai Summer Undergraduate Research Program .

Mount Sinai Medical Center is an equal opportunity/affirmative action employer.

More information

Please contact Jonathan .